Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy.
INTRODUCTION: Compounds exhibiting low non-specific intracellular binding or non-stickiness are concomitant with rapid clearing and in high demand for live-cell imaging assays because they allow for intracellular receptor localization with a high signal/noise ratio.The CLA (Conjugated Linoleic Acid) non-stickiness property is particularly important